[Orofacial disformation in thalassemia patients refered to Kerman special disease center in 2007]

Major beta thalassemia has been reported as a high prevalence genetic disorder in Iran with some oromaxillofacial complications. The aim of this study was to evaluate the prevalence of oromaxillofacial disorder in thalassemia patients at Kerman province. In this research, 208 patients with major beta thalassemia were under study. Data were obtained by oral examination and analyzed by statistical programs of SPSS 13.5, t- test, and X[2] test. Out of 208 patients with major beta thalassemia, 103 were male and 105 female. The mean age was 12.48 with the range of 1-26 years. The most prevalent facies appearance in these patients was pale face [47.3%] and lower jaw protrusion had the minimum prevalence. From data analysis, it was found that 46.6% of patients had protrusion of maxilla. Results of the present study showed that the most prevalent location with pigmentation into oral cavity was gingival of labial and the locations with less prevalence were lateral border of tongue, soft palate, and floor of mouth. This study showed that about 84.2% [175 cases] of all patients under consideration complained from changes in oral and Maxillofacial complications including upper and lower jaw protrusion, saddle nose, space between anterior teeth, anterior teeth protrusion, posterior malocclusion and frontal bossing. Also, it was revealed that the rate of prevalence for oral and Maxillofacial complications decreases when patients receive blood at younger ages

[ prevalence of central papillary atrophy in volunteer students of Kerman university of medical sciences [2006]]

Median rhomboid glossitis [MRG] or central papillary atrophy is an uncommon benign abnormality of the tongue, most frequently affecting men and it is believed that candidacies is the major etiologic factor for this abnormality. The purpose of this study was to investigate the prevalence of MRG and its characteristics in 837 students in Kerman University of Medical Sciences. In this research, 837 Medical Sciences students in 2006 were selected by census sampling and enrolled into the study. Oral examinations were performed in classes, wards and dormitories. All characteristics of subjects were recorded in a researcher-mode form and in those who had MRG based on clinical diagnosis, a sample was taken by swab and sent to the laboratory for candidiasis infection [hypha]. Data were analyzed by SPSS 13.5 and using t-test and chi2 test. The results showed that the prevalence of MRG is about 1.5% [13 cases]. There was a relationship between MRG and sex, but there was no relation between MRG and age. In 11 cases [84.6%] the smears were positive for candidiasis infection [hypha]. Based on previous published studies in the past and the present study, candidiasis infection [hypha] is a main factor for MRG. Therefore, in the cases of having median rhomboid glossitis, all causing factors for candidiasis should be examined and removed